Indications

Prolia® is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well.

Prolia® is a prescription medicine used to increase bone mass in men with osteoporosis who are at high risk for fracture.

Prolia® is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines (such as prednisone) for at least six months and are at high risk for fracture.

Prolia® is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments for prostate cancer that has not spread to other parts of the body.

Prolia® is a prescription medicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body.

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Can’t get to your doctor? Don’t worry, you may still be able to get your Prolia®

If you currently take Prolia® and receiving your next regular dose is being disrupted by COVID-19 closures, there may be other options that you and your doctor can consider through ProliaFinder.com or the Prolia® At-Home Nurse Injection Program (currently available in New York and Washington states).

EXPLORE YOUR OPTIONS
ProliaFinder.com

For existing Prolia® patients who need help getting their next injection, there might be alternate sites of care. ProliaFinder.com is a website that can be used by healthcare professionals to find alternate sites of care where they can send patients to get Prolia® administered. It’s not a website that is designed for patient interaction, but it can be a useful reference as you and your doctor work together to get your next dose in the event your doctor’s office is not an option.

How to learn more about ProliaFinder.com and alternate sites of care

Step 1:

Visit ProliaFinder.com and enter your ZIP code.

Step 2:

Write down the list of alternate site of care locations near you.

Step 3:

Talk to your doctor to discuss alternative ways you might be able to receive your next Prolia® dose. Ask your doctor about referring you to one of the alternate site of care locations on your list to receive your Prolia® dose.

Prolia® At-Home Nurse Injection Program (Currently in New York and Washington States)

For existing Prolia® patients who need help getting their next injection, there might be an At-Home Nurse Injection option. For existing Prolia® patients in New York or Washington state who are currently restricted to their homes and/or do not have an available treatment site in their area, a short-term option is available.

In a number of states where the COVID-19 impact is severe, Amgen is making a Prolia® At-Home Nurse Injection Program option available to existing Prolia® patients who are currently restricted to their homes and/or do not have an available treatment site in their area. During the COVID-19 crisis, Amgen is partnering locally to offer the Prolia® At-Home Nurse Injection Program in: 

  • New York
  • Washington

How to learn more about the Prolia® At-Home Nurse Injection Program

Step 1:

If you live in New York or Washington state, ask your doctor about Prolia® At-Home Nurse Injection Program availability and eligibility.

Step 2:

Your doctor can find out more about the Prolia® At-Home Nurse Injection Program by contacting his or her Prolia® representative or Amgen at 800-77-AMGEN (800-772-6436).

Step 3:

Your doctor will initiate the process to determine if you are eligible for home injection, as certain eligibility requirements apply.

DISCUSS YOUR OPTIONS WITH YOUR DOCTOR

We want to help make staying on your treatment schedule as simple and safe as possible for you. Our doctor discussion guide offers some questions you may want answers to right now that will help start a conversation with your doctor.

Questions for your doctor
  • Will delaying my next dose impact my risk for fracture?
  • Can I keep my scheduled appointment, or make an appointment with you now?
  • Can you tell me about new public health guidelines or procedures your office is following to help keep us all safe? For example, will the waiting room be limited? Can I make an early morning appointment? Should I wear a mask?
  • If you are not taking in-person appointments, can you help me make other arrangements?

Click below to download the guide and make notes. Download Guide download icon download icon white

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Important Safety Information

Do not take Prolia® if you: have low blood calcium; or are pregnant or plan to become pregnant, as Prolia® may harm your unborn baby; or are allergic to denosumab or any ingredients in Prolia®.
What is the most important information I should know about Prolia®?
If you receive Prolia®, you should not receive XGEVA®. Prolia® contains the same medicine as XGEVA® (denosumab).
Prolia® can cause serious side effects:
Serious allergic reactions have happened in people who take Prolia®. Call your doctor or go to your nearest emergency room right away if you have any symptoms of a serious allergic reaction, including low blood pressure (hypotension); trouble breathing; throat tightness; swelling of your face, lips, or tongue; rash; itching; or hives.
Low blood calcium (hypocalcemia). Prolia® may lower the calcium levels in your blood. If you have low blood calcium, it may get worse during treatment. Your low blood calcium must be treated before you receive Prolia®.
Take calcium and vitamin D as your doctor tells you to help prevent low blood calcium.
Severe jaw bone problems (osteonecrosis) may occur. Your doctor should examine your mouth before you start Prolia® and may tell you to see your dentist. It is important for you to practice good mouth care during treatment with Prolia®.
Unusual thigh bone fractures. Some people have developed unusual fractures in their thigh bone. Symptoms of a fracture include new or unusual pain in your hip, groin, or thigh.
Increased risk of broken bones, including broken bones in the spine, after stopping, skipping or delaying Prolia®. Talk with your doctor before starting Prolia® treatment. After your treatment with Prolia® is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. Your risk for having more than 1 broken bone in your spine is increased if you have already had a broken bone in your spine. Do not stop, skip or delay taking Prolia® without first talking with your doctor. If your Prolia® treatment is stopped, talk to your doctor about other medicine that you can take.
Serious infections in your skin, lower stomach area (abdomen), bladder, or ear may happen. Inflammation of the inner lining of the heart (endocarditis) due to an infection may also happen more often in people who take Prolia®. You may need to go to the hospital for treatment.
Prolia® is a medicine that may affect the ability of your body to fight infections. People who have weakened immune systems or take medicines that affect the immune system may have an increased risk for developing serious infections.
Skin problems such as inflammation of your skin (dermatitis), rash, and eczema have been reported.
Bone, joint, or muscle pain. Some people who take Prolia® develop severe bone, joint, or muscle pain.
Before taking Prolia®, tell your doctor about all of your medical conditions, including if you:
  • Take the medicine XGEVA® (denosumab)
  • Have low blood calcium
  • Cannot take daily calcium and vitamin D
  • Had parathyroid or thyroid surgery (glands located in your neck)
  • Have been told you have trouble absorbing minerals in your stomach or intestines (malabsorption syndrome)
  • Have kidney problems or are on kidney dialysis
  • Are taking medicine that can lower your blood calcium levels
  • Plan to have dental surgery or teeth removed
  • Are pregnant or plan to become pregnant
    Females who are able to become pregnant:
    • Your healthcare provider should do a pregnancy test before you start treatment with Prolia®.
    • You should use an effective method of birth control (contraception) during treatment with Prolia® and for at least 5 months after your last dose of Prolia®.
    • Tell your doctor right away if you become pregnant while taking Prolia®.
  • Are breast-feeding or plan to breast-feed

What are the possible side effects of Prolia®?

It is not known if the use of Prolia® over a long period of time may cause slow healing of broken bones. The most common side effects of Prolia® in women being treated for osteoporosis after menopause are back pain, pain in your arms and legs, high cholesterol, muscle pain, and bladder infection.

The most common side effects of Prolia® in men with osteoporosis are back pain, joint pain, and common cold (runny nose or sore throat).

The most common side effects of Prolia® in patients with corticosteroid-induced osteoporosis are back pain, high blood pressure, lung infection (bronchitis), and headache.

The most common side effects of Prolia® in patients receiving certain treatments for prostate or breast cancer are joint pain, back pain, pain in your arms and legs, and muscle pain. Additionally, in Prolia®-treated men with nonmetastatic prostate cancer receiving ADT, a greater incidence of cataracts was observed.

These are not all the possible side effects of Prolia®. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. 

Indications

Prolia® is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk for fracture or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well.

Prolia® is a prescription medicine used to increase bone mass in men with osteoporosis who are at high risk for fracture.

Prolia® is a prescription medicine used to treat osteoporosis in men and women who will be taking corticosteroid medicines (such as prednisone) for at least six months and are at high risk for fracture.

Prolia® is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments for prostate cancer that has not spread to other parts of the body.

Prolia® is a prescription medicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments for breast cancer that has not spread to other parts of the body.

Please see Prolia® full Prescribing Information and Medication Guide.

Important Safety Information

Do not take Prolia® if you: have low blood calcium; or are pregnant or plan to become pregnant, as Prolia® may harm your unborn baby; or are allergic to denosumab or any ingredients in Prolia®.
What is the most important information I should know about Prolia®?
If you receive Prolia®, you should not receive XGEVA®. Prolia® contains the same medicine as XGEVA® (denosumab). 
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